Dimethyl Sulfoxide → 1-Cyclopropyl-6-fluoro-8-methoxy-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

HRID 206639

Reaction equation

[CH3:22][N:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[CH3:29][S:30]([CH3:31])=[O:32].[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([F:16])[c:12]([O:14][CH3:15])[c:13]23)[CH2:2][CH2:3]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:19](=[O:20])[OH:21])[c:7](=[O:18])[c:8]3[cH:9][c:10]([F:17])[c:11]([N:26]4[CH2:25][CH2:24][N:23]([CH3:22])[CH2:28][CH2:27]4)[c:12]([O:14][CH3:15])[c:13]23)[CH2:2][CH2:3]1

Participants

Reactant 3

HCID 679Dimethyl Sulfoxide

HCID 531671-Methylpiperazine

HCID 70194651-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

Product 1

HCID 107382321-Cyclopropyl-6-fluoro-8-methoxy-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Sources & evidence

ORD record: ord-051185ebfd494c11a3711e2685599958
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Linked notes

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