HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

Hydrochloric Acid → HCID 68412886, compound

HRID 2070163
Notes
Print preview

Reaction equation

HRID 2070163 reaction equation
[NH2:1][C:2]([CH3:45])([CH3:44])[C:3]([NH:5][C@H:6]([CH2:33][C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[N:36]([CH3:43])[CH:35]=1)[C:7](=[O:32])[NH:8][CH:9]1[CH2:18][C:17]2[C:12](=[C:13]([N:19]3[CH2:23][CH2:22][CH2:21][C:20]3=[O:24])[CH:14]=[CH:15][CH:16]=2)[N:11]([CH2:25][C:26]2[CH:30]=[CH:29][S:28][CH:27]=2)[C:10]1=[O:31])=[O:4].[ClH:46]>C(O)C>[ClH:46].[NH2:1][C:2]([CH3:45])([CH3:44])[C:3]([NH:5][C@H:6]([CH2:33][C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[CH:40][CH:41]=2)[N:36]([CH3:43])[CH:35]=1)[C:7](=[O:32])[NH:8][CH:9]1[CH2:18][C:17]2[C:12](=[C:13]([N:19]3[CH2:23][CH2:22][CH2:21][C:20]3=[O:24])[CH:14]=[CH:15][CH:16]=2)[N:11]([CH2:25][C:26]2[CH:30]=[CH:29][S:28][CH:27]=2)[C:10]1=[O:31])=[O:4]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 59620360HCID 59620360, compound

Product 1

HCID 68412886HCID 68412886, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Amino-2-methyl-N-[(2R)-3-(1-methyl-1H-indol-3-yl)-1-oxo-1-[2-oxo-8-(2-oxopyrrolidin-1-yl)-1-(thiophen-3-ylmethyl)-1,2,3,4-tetrahydroquinolin-3-ylamino]propan-2-yl]propanamide (116 mg) was dissolved in ethanol (1.0 mL), and 1N hydrochloric acid (161 μL) was added thereto. Subsequently, the solvent was evaporated under reduced pressure, whereby the title compound (103 mg) was yielded.

Workup

  1. customSubsequently, the solvent was evaporated under reduced pressure, whereby the title compound (103 mg)
  2. customwas yielded

Sources & evidence

ORD record
ord-e6ba3596ff9048228396288b76c5b7ec
Source dataset
uspto-grants-2012_10
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US08299255B2

Reaction notes

Loading…

On this pageParticipantsProcedureWorkupSources & evidenceReaction notes