Hydrochloric Acid → 3-[N-(2-Cyclohexylethyl)amino]propionamide hydrochloride
Reaction equation
[ClH:1].C(OC([N:9]([CH2:18][CH2:19][C:20]([NH2:22])=[O:21])[CH2:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=O)(C)(C)C>O1CCOCC1>[ClH:1].[CH:12]1([CH2:11][CH2:10][NH:9][CH2:18][CH2:19][C:20]([NH2:22])=[O:21])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Next, a 4 N solution of hydrogen chloride in 1,4-dioxane (3.1 ml) was added to 3-[N-(t-butoxycarbonyl)-N-(2-cyclohexylethyl)amino]propionamide (0.37 g, 1.2 mmol), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, diisopropyl ether was added to the resulting solid, and the solid was filtered off to give 0.30 g (quantitatively) of the titled compound as colorless crystals.