Methanol → 2,5-dichloro-N-(2-(difluoromethylsulfonyl)phenyl)-pyrimidin-4-amine
Reaction equation
[CH3:28][OH:29].[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:9])[c:6]([Cl:8])[n:7]1.[Cl:25][CH2:26][Cl:27].[F:10][CH:11]([S:12](=[O:13])(=[O:14])[c:15]1[c:16]([NH2:17])[cH:18][cH:19][cH:20][cH:21]1)[F:22].[H-:23].[Na+:24].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:9])[c:6]([NH:17][c:16]2[c:15]([S:12]([CH:11]([F:10])[F:22])(=[O:13])=[O:14])[cH:21][cH:20][cH:19][cH:18]2)[n:7]1Participants
8
Sources & evidence
- ORD record
- ord-ba8e2202a1b04b08aefbd57de7d9b581
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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