Iodoethane → 4-Ethoxycyclohexan-1-one

HRID 2089174Notes

Reaction equation

[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([OH:11])[CH2:7][CH2:6]2)O[CH2:3][CH2:2]1.C(I)C>>[CH2:2]([O:1][CH:5]1[CH2:10][CH2:9][C:8](=[O:11])[CH2:7][CH2:6]1)[CH3:3]

Participants

Reactant 2

HCID 6340Iodoethane

HCID 5673521,4-Dioxaspiro(4.5)decan-8-ol

Product 1

HCID 5464704-Ethoxycyclohexan-1-one

Procedure

The title compound was prepared as white solid from reaction of 1,4-dioxa-spiro[4.5]decan-8-ol and EtI (Aldrich) followed by de-protection using the procedure described in Example 34.

Sources & evidence

ORD record: ord-0f10986f02b247f1b0ebfacf4f0f3ce2
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436023B2

Reaction notes

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