Acetone → 5-Bromo-4-Chloro-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine

HRID 209045

Reaction equation

HRID 209045 reaction equation
[Br:1][c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12.[CH3:25][C:26](=[O:27])[CH3:28].[Na+:24].[OH-:23].[c:12]1([CH3:22])[cH:13][cH:14][c:15]([S:18](=[O:19])(=[O:20])[Cl:21])[cH:16][cH:17]1>>[Br:1][c:2]1[cH:3][n:4]([S:18]([c:15]2[cH:14][cH:13][c:12]([CH3:22])[cH:17][cH:16]2)(=[O:19])=[O:20])[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12

Participants

6

Reactant 5

HCID 180AcetoneHCID 923Sodium ionHCID 961HydroxideHCID 73974-Toluenesulfonyl chlorideHCID 53807105-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 577502825-Bromo-4-Chloro-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine

Sources & evidence

ORD record
ord-2448b128eae84240b18978116baf88f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…