Ethyl 2-[(prop-2-en-1-yl)amino]-1,3-thiazole-4-carboxylate → HCID 15053559, compound

HRID 2107282

Reaction equation

HRID 2107282 reaction equation
[CH2:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([C:10](OCC)=[O:11])[N:9]=1)[CH:2]=[CH2:3].[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH2:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([CH2:10][OH:11])[N:9]=1)[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 7171906Ethyl 2-[(prop-2-en-1-yl)amino]-1,3-thiazole-4-carboxylateHCID 21226445Aluminium lithium hydride

Product 1

HCID 15053559HCID 15053559, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction described in Preparation 15 was repeated, but using 10 g of ethyl 2-allylaminothiazole-4-carboxylate, 2.7 g of lithium aluminum hydride and 150 ml of tetrahydrofuran. giving the title compound as pale brown needles.

Workup

  1. customThe reaction described in Preparation 15

Sources & evidence

ORD record
ord-96b70246f9234f0a9c9bdb303be4c2c6
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Linked notes

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