Water → N-[5-chloro-2-hydroxy-4-trifluoromethylphenyl]isonicotinamide

HRID 211194

Reaction equation

HRID 211194 reaction equation
[NH2:1][c:2]1[c:3]([OH:13])[cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[cH:7]1.[OH2:29].[OH:14][C:15](=[O:16])[c:17]1[cH:18][cH:19][n:20][cH:21][cH:22]1.[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1>>[NH:1]([c:2]1[c:3]([OH:13])[cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[cH:7]1)[C:15](=[O:14])[c:17]1[cH:18][cH:19][n:20][cH:21][cH:22]1

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 5922Isonicotinic AcidHCID 668804782-Amino-4-chloro-5-(trifluoromethyl)phenol

Product 1

HCID 66879747N-[5-chloro-2-hydroxy-4-trifluoromethylphenyl]isonicotinamide

Sources & evidence

ORD record
ord-cb48b9cbd2614404af8c379145678e1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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