Sodium ion → tert-Butyl 4-((3-(5-methyl-1H-tetrazol-1-yl)-5-(trifluoromethyl)benzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

HRID 211247

Reaction equation

HRID 211247 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5](-[n:13]2[n:14][n:15][n:16][c:17]2[CH3:18])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[H-:40].[Na+:41].[OH2:47].[OH:19][CH2:20][C:21]1([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]1>>[CH2:2]([c:3]1[cH:4][c:5](-[n:13]2[n:14][n:15][n:16][c:17]2[CH3:18])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)[O:19][CH2:20][C:21]1([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 166653HydrideHCID 9994433Tert-butyl 4-(hydroxymethyl)-4-phenylpiperidine-1-carboxylateHCID 589934921-(3-bromomethyl-5-trifluoromethyl-phenyl)-5-methyl-1H-tetrazole

Product 1

HCID 58993687tert-Butyl 4-((3-(5-methyl-1H-tetrazol-1-yl)-5-(trifluoromethyl)benzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-c7c4b8a932ef480cabb5011edc94901e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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