2-Chlorobenzaldehyde → (2-Amino-5-methoxy-4-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone
Reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[CH3:10][O:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[CH:14][C:13]=1[O:19][CH2:20][CH2:21][O:22][CH3:23]>>[NH2:16][C:15]1[CH:14]=[C:13]([O:19][CH2:20][CH2:21][O:22][CH3:23])[C:12]([O:11][CH3:10])=[CH:18][C:17]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]Participants
3
Procedure
(2-amino-5-methoxy-4-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone (Xgg) was prepared by reacting 2-chlorobenzaldehyde with 0.0296 moles of 4-methoxy-3-(2-methoxyethoxy) aniline in a manner analogous to Example 1. MH+/Z=336.
Sources & evidence
- ORD record
- ord-1e038c1b12e7434dbe3b8ab2ba81a0f4
- Source dataset
- uspto-grants-2009_04
- Patent number
- US07524840B2