Dimethylformamide → N-[4-fluoro-2-(oxiran-2-ylmethoxy)phenyl]acetamide

HRID 211545

Reaction equation

HRID 211545 reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[Cs+:34].[Cs+:35].[F:1][c:2]1[cH:3][c:4]([OH:12])[c:5]([NH:8][C:9]([CH3:10])=[O:11])[cH:6][cH:7]1.[O:13]1[CH:14]([CH2:16][O:17][S:18]([c:19]2[cH:20][cH:21][cH:22][c:23]([N+:24]([O-:25])=[O:26])[cH:27]2)(=[O:28])=[O:29])[CH2:15]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[F:1][c:2]1[cH:3][c:4]([O:12][CH2:16][CH:14]2[O:13][CH2:15]2)[c:5]([NH:8][C:9]([CH3:10])=[O:11])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 177738N-(4-fluoro-2-hydroxyphenyl)acetamideHCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate

Product 1

HCID 22386940N-[4-fluoro-2-(oxiran-2-ylmethoxy)phenyl]acetamide

Sources & evidence

ORD record
ord-e6bc07848d3c4e0d8ecc9aaf9c18e29a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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