Methanol → 1-Bromo-5-chloro-3-fluoro-2-isocyanatobenzene

Reaction equation

[Br:1][c:2]1[c:3]([NH2:4])[c:5]([F:10])[cH:6][c:7]([Cl:9])[cH:8]1.[C:11]([O:12][C:19]([Cl:20])([Cl:21])[Cl:22])(=[O:13])[O:14][C:15]([Cl:16])([Cl:17])[Cl:18].[CH2:23]1[O:24][CH2:25][CH2:26][O:27][CH2:28]1.[CH3:29][OH:30]>>[Br:1][c:2]1[c:3]([N:4]=[C:11]=[O:12])[c:5]([F:10])[cH:6][c:7]([Cl:9])[cH:8]1

Participants

Reactant 4

HCID 887Methanol

HCID 312751,4-Dioxane

HCID 94429Triphosgene

HCID 27362222-Bromo-4-chloro-6-fluoroaniline

Product 1

HCID 866189411-Bromo-5-chloro-3-fluoro-2-isocyanatobenzene

Sources & evidence

ORD record: ord-ba2a597d91ae41828b68ee48a681faf1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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