Dichloromethane → Methyl 2-amino-3-[4-(2,6-naphthyridin-1-yloxy)phenyl]propanoate

HRID 212370

Reaction equation

HRID 212370 reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9]([O:12][c:13]2[n:14][cH:15][cH:16][c:17]3[cH:18][n:19][cH:20][cH:21][c:22]23)[cH:10][cH:11]1)[NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])=[O:31].[Cl:39][CH2:40][Cl:41].[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9]([O:12][c:13]2[n:14][cH:15][cH:16][c:17]3[cH:18][n:19][cH:20][cH:21][c:22]23)[cH:10][cH:11]1)[NH2:23])=[O:31]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69375347Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(2,6-naphthyridin-1-yloxy)phenyl]propanoate

Product 1

HCID 69378473Methyl 2-amino-3-[4-(2,6-naphthyridin-1-yloxy)phenyl]propanoate

Sources & evidence

ORD record
ord-d0993312f17e442a873868bcc0df5514
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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