Potassium Cation → Tert-butyl 9-oxo-7-oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylate

Reaction equation

[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:22][C:23]([CH3:24])([O-:25])[CH3:26].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][CH2:6][CH2:7][C:8]1([OH:21])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]1.[K+:27]>>[CH2:2]1[C:3](=[O:4])[NH:5][CH2:6][CH2:7][C:8]2([CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[O:21]1

Participants

Reactant 4

HCID 813Potassium Cation

HCID 8028Tetrahydrofuran

HCID 45749132-Methylpropan-2-olate

HCID 57989111tert-Butyl 4-(2-(2-chloroacetamido)ethyl)-4-hydroxypiperidine-1-carboxylate

Product 1

HCID 57989131Tert-butyl 9-oxo-7-oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylate

Sources & evidence

ORD record: ord-7ef6244c70b3481c8a01ef0bd27d1734
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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