Tetrahydrofuran → 1-[[4-Chloro-5-(chloromethylsulfonylamino)-2-fluorophenyl]carbamoyl]-4-fluoropyrrolidine-2-carboxylic acid

HRID 2126368

Reaction equation

HRID 2126368 reaction equation
[Cl:1][CH2:2][S:3](=[O:4])(=[O:5])[NH:6][c:7]1[c:8]([Cl:17])[cH:9][c:10]([F:16])[c:11]([N:13]=[C:14]=[O:15])[cH:12]1.[F:18][CH:19]1[CH2:20][CH:21]([C:24](=[O:25])[OH:26])[NH:22][CH2:23]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][CH2:2][S:3](=[O:4])(=[O:5])[NH:6][c:7]1[c:8]([Cl:17])[cH:9][c:10]([F:16])[c:11]([NH:13][C:14](=[O:15])[N:22]2[CH:21]([C:24](=[O:25])[OH:26])[CH2:20][CH:19]([F:18])[CH2:23]2)[cH:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 5603404-Fluoropyrrolidine-2-carboxylic acidHCID 110774021-chloro-N-(2-chloro-4-fluoro-5-isocyanatophenyl)methanesulfonamide

Product 1

HCID 187608411-[[4-Chloro-5-(chloromethylsulfonylamino)-2-fluorophenyl]carbamoyl]-4-fluoropyrrolidine-2-carboxylic acid

Sources & evidence

ORD record
ord-9011f56144174b54b2d135850e331429
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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