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Tetrahydrofuran → 4-Methyl-1-[[3-[[1-[2-(1-methylethoxy)phenyl]-4-piperazinyl]methyl]phenyl]methyl]piperidine-2,6-dione

HRID 2127484
Notes
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Reaction equation

HRID 2127484 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:1][CH:2]([CH3:3])[O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[cH:19][c:20]([CH2:21][NH2:22])[cH:23][cH:24][cH:25]3)[CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1.[CH3:26][CH:27]1[CH2:28][C:29](=[O:30])[O:31][C:32](=[O:34])[CH2:33]1>>[CH3:1][CH:2]([CH3:3])[O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[cH:19][c:20]([CH2:21][N:22]4[C:29](=[O:30])[CH2:28][CH:27]([CH3:26])[CH2:33][C:32]4=[O:31])[cH:23][cH:24][cH:25]3)[CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1
ParticipantsSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 778283-Methylglutaric anhydrideHCID 10521066HCID 10521066, compound

Product 1

HCID 108372254-Methyl-1-[[3-[[1-[2-(1-methylethoxy)phenyl]-4-piperazinyl]methyl]phenyl]methyl]piperidine-2,6-dione

Sources & evidence

ORD record
ord-c5df7b74b30343a68fc31c7af6b6eed1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes