Acetic Acid → 2-Bromo-1-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)ethanone

Reaction equation

[Br:20][Br:21].[BrH:26].[CH3:27][C:28](=[O:29])[OH:30].[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([C:11]([CH3:12])=[O:13])[s:10]2.[Cl:22][CH:23]([Cl:24])[Cl:25]>>[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([C:11]([CH2:12][Br:20])=[O:13])[s:10]2

Participants

Reactant 5

HCID 176Acetic Acid

HCID 260Hydrogen Bromide

HCID 6212Chloroform

HCID 24408Bromine

HCID 595931571-(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)ethanone

Product 1

HCID 595929052-Bromo-1-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)ethanone

Sources & evidence

ORD record: ord-d3e41049c28840d487dd6786dcc5361f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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