Dichloromethane → Tert-butyl 4-[2-[5-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]acetyl]amino]-6-methyl-1-oxoisoquinolin-2-yl]propyl]piperazine-1-carboxylate
Reaction equation
[CH2:56]([Cl:57])[Cl:58].[CH3:1][S:2]([O:3][CH2:6][CH:7]([CH3:8])[n:9]1[c:10](=[O:35])[c:11]2[cH:12][cH:13][c:14]([CH3:34])[c:15]([NH:19][C:20]([CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)=[O:33])[c:16]2[cH:17][cH:18]1)(=[O:4])=[O:5].[CH3:49][CH2:50][N:51]([CH2:52][CH3:53])[CH2:54][CH3:55].[N:36]1([C:42](=[O:43])[O:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1>>[CH2:6]([CH:7]([CH3:8])[n:9]1[c:10](=[O:35])[c:11]2[cH:12][cH:13][c:14]([CH3:34])[c:15]([NH:19][C:20]([CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)=[O:33])[c:16]2[cH:17][cH:18]1)[N:39]1[CH2:38][CH2:37][N:36]([C:42](=[O:43])[O:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:41][CH2:40]1Participants
5
