Water → N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]acetamide

HRID 2137883

Reaction equation

[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[CH3:32][C:33]([Cl:34])=[O:35].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1.[OH2:36].[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1)[C:33]([CH3:32])=[O:35]

Participants

Reactant 6

HCID 962Water

HCID 1049Pyridine

HCID 1140Toluene

HCID 6228Dimethylformamide

HCID 6367Acetyl chloride

HCID 102210654-[4-(4-Aminophenyl)piperazin-1-yl]phenol

Product 1

HCID 15125497N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]acetamide

Sources & evidence

ORD record: ord-c33e5570946e46379003184f74bc84dc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Linked notes

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