S-[(N,N-dibenzyl)aminobutyl]isothiourea, hydrochloride → Dibenzylamine

HRID 21380

Reaction equation

HRID 21380 reaction equation
Cl.[CH2:2]([N:9](CCCCSC(=N)N)[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>[OH-].[Na+]>[CH2:10]([NH:9][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 1

HCID 131719016S-[(N,N-dibenzyl)aminobutyl]isothiourea, hydrochloride

Product 1

HCID 7656Dibenzylamine

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

S-[(N,N-dibenzyl)aminobutyl]isothiourea, hydrochloride (prepared according to Example 15) was hydrolysed in aqueous ethanolic sodium hydroxide. The solvents were evaporated and the residue taken up in water and extracted 3 times with methylene dichloride. The extracts were dried (MgSO4), filtered and evaporated to give N-(3-mercaptopropy])dibenzylamine.

Workup

  1. customThe solvents were evaporated
  2. extractionextracted 3 times with methylene dichloride
  3. dry with materialThe extracts were dried (MgSO4)
  4. filtrationfiltered
  5. customevaporated

Sources & evidence

ORD record
ord-dfd2f0be67984e6aabe343adb657573f
Source dataset
uspto-grants-1995_06
Patent number
US05422355

Linked notes

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