Phosphorus oxychloride → 4-Chloro-6-(4-bromophenyl)thieno[3,2-c]pyridine

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([c:12](=[O:14])[nH:13]2)[cH:15][cH:16][s:17]3)[cH:6][cH:7]1.[P:18]([Cl:19])([Cl:20])([Cl:21])=[O:22]>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([c:12]([Cl:20])[n:13]2)[cH:15][cH:16][s:17]3)[cH:6][cH:7]1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 225024536-(4-bromophenyl)-5H-thieno[3,2-c]pyridin-4-one

Product 1

HCID 225035574-Chloro-6-(4-bromophenyl)thieno[3,2-c]pyridine

Sources & evidence

ORD record: ord-8627996623d64c94ad15dea5438e9a3e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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