Hydrochloric Acid → 2-[4-Chloro-3-(1-fluoroethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([CH:9]([CH3:10])[F:11])[c:5]([Cl:8])[cH:6][cH:7]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[CH:17]([O:18][B:21]1[O:22][C:23]([CH3:28])([CH3:29])[C:24]([CH3:26])([CH3:27])[O:25]1)([CH3:19])[CH3:20].[ClH:30].[OH2:36]>>[c:2]1([B:21]2[O:22][C:23]([CH3:28])([CH3:29])[C:24]([CH3:26])([CH3:27])[O:25]2)[cH:3][c:4]([CH:9]([CH3:10])[F:11])[c:5]([Cl:8])[cH:6][cH:7]1

Participants

Reactant 6

HCID 313Hydrochloric Acid

HCID 962Water

HCID 3283Diethyl Ether

HCID 50177412-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HCID 591269474-Bromo-1-chloro-2-(1-fluoroethyl)benzene

HCID 178418339Butyllithium

Product 1

HCID 59126938

Sources & evidence

ORD record: ord-660c0042b6ce442b9f021b6bd6808ff2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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