Borane → (4-Pentafluoroethyl-benzyl)-[2-(3-trifluoromethyl-phenyl)-ethyl]-amine

Reaction equation

[BH3:6].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[F:7][C:8]([C:9]([F:10])([F:11])[F:12])([c:13]1[cH:14][cH:15][c:16]([CH2:17][NH:18][C:19]([CH2:20][c:21]2[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]2)=[O:31])[cH:32][cH:33]1)[F:34].[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1>>[F:7][C:8]([C:9]([F:10])([F:11])[F:12])([c:13]1[cH:14][cH:15][c:16]([CH2:17][NH:18][CH2:19][CH2:20][c:21]2[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]2)[cH:32][cH:33]1)[F:34]

Participants

Reactant 3

HCID 6331Borane

HCID 8028Tetrahydrofuran2×

HCID 86615229N-(4-pentafluoroethyl-benzyl)-2-(3-trifluoromethyl-phenyl)-acetamide

Product 1

HCID 86615230(4-Pentafluoroethyl-benzyl)-[2-(3-trifluoromethyl-phenyl)-ethyl]-amine

Sources & evidence

ORD record: ord-f1da872a924740a6a996c1f43becf0cd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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