Water → 2-chloro-5-[1,4-dimethyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-4-fluorobenzenemethanol

Reaction equation

[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8](-[c:12]2[n:13][n:14]([CH3:22])[c:15]([C:18]([F:19])([F:20])[F:21])[c:16]2[CH3:17])[c:9]([F:11])[cH:10]1.[OH2:23]>>[Cl:1][c:2]1[c:3]([CH2:4][OH:5])[cH:7][c:8](-[c:12]2[n:13][n:14]([CH3:22])[c:15]([C:18]([F:19])([F:20])[F:21])[c:16]2[CH3:17])[c:9]([F:11])[cH:10]1

Participants

Reactant 3

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 229064292-Chloro-5-[1,4-dimethyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-4-fluorobenzoic acid

Product 1

HCID 229064162-chloro-5-[1,4-dimethyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-4-fluorobenzenemethanol

Sources & evidence

ORD record: ord-2a0d3ce6c98541cabd11b4472260aed3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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