Hydrochloric Acid → N1-Methyl-5-(2-amino-5-cyano-4-pyridyl)amino-1H-1-indolecarboxamide

Reaction equation

[CH2:11]([O:12][CH:13]([OH:14])[CH3:15])[CH3:16].[CH3:24][NH:25][C:26](=[O:27])[n:28]1[cH:29][cH:30][c:31]2[cH:32][c:33]([NH2:37])[cH:34][cH:35][c:36]12.[ClH:17].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:9]#[N:10])[c:6]([Cl:8])[cH:7]1.[n:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:9]#[N:10])[c:6]([NH:37][c:33]2[cH:32][c:31]3[cH:30][cH:29][n:28]([C:26]([NH:25][CH3:24])=[O:27])[c:36]3[cH:35][cH:34]2)[cH:7]1

Participants

Reactant 5

HCID 313Hydrochloric Acid

HCID 1049Pyridine

HCID 101298981-Ethoxyethanol

HCID 21949101N1-Methyl-5-amino-1H-1-indolecarboxamide

HCID 219492196-Amino-4-chloro-3-pyridinecarbonitrile

Product 1

HCID 21949356N1-Methyl-5-(2-amino-5-cyano-4-pyridyl)amino-1H-1-indolecarboxamide

Sources & evidence

ORD record: ord-6878e5078d174266a02c6e0b0c6a63ab
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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