Water → 6-(6-chloropyrimidin-4-yl)oxy-N-[4-fluoro-3-(trifluoromethyl)phenyl]isoquinoline-1-carboxamide
Reaction equation
[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[Cl:1][c:2]1[cH:3][c:4]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][n:14][c:15]([C:19](=[O:20])[Cl:21])[c:16]3[cH:17][cH:18]2)[n:5][cH:6][n:7]1.[Cl:44][CH2:45][Cl:46].[F:22][c:23]1[c:24]([C:30]([F:31])([F:32])[F:33])[cH:25][c:26]([NH2:27])[cH:28][cH:29]1.[OH2:43]>>[Cl:1][c:2]1[cH:3][c:4]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][n:14][c:15]([C:19](=[O:20])[NH:27][c:26]4[cH:25][c:24]([C:30]([F:31])([F:32])[F:33])[c:23]([F:22])[cH:29][cH:28]4)[c:16]3[cH:17][cH:18]2)[n:5][cH:6][n:7]1
