Dichloromethane → N-(4-{4-[7-(4-cyano-3-trifluoromethylphenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3,4]oct-5-yl]phenyl}-butanoyl)-methanesulfonamide
Reaction equation
[C:1](#[N:2])[c:3]1[c:4]([C:31]([F:32])([F:33])[F:34])[cH:5][c:6]([N:9]2[C:10](=[S:30])[N:11]([c:18]3[cH:19][cH:20][c:21]([CH2:24][CH2:25][CH2:26][C:27](=[O:28])[OH:29])[cH:22][cH:23]3)[C:12]3([CH2:13][CH2:14][CH2:15]3)[C:16]2=[O:17])[cH:7][cH:8]1.[CH3:47][S:48](=[O:49])(=[O:50])[NH2:51].[CH3:52][N:53]([CH3:54])[c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1.[Cl:35][c:36]1[cH:37][c:38]([Cl:39])[cH:40][c:41]([Cl:42])[c:43]1[C:44]([Cl:45])=[O:46].[Cl:61][CH2:62][Cl:63]>>[C:1](#[N:2])[c:3]1[c:4]([C:31]([F:32])([F:33])[F:34])[cH:5][c:6]([N:9]2[C:10](=[S:30])[N:11]([c:18]3[cH:19][cH:20][c:21]([CH2:24][CH2:25][CH2:26][C:27](=[O:29])[NH:51][S:48]([CH3:47])(=[O:49])=[O:50])[cH:22][cH:23]3)[C:12]3([CH2:13][CH2:14][CH2:15]3)[C:16]2=[O:17])[cH:7][cH:8]1
