Hydrochloric Acid → 7-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butoxy]-5-trifluoromethyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one

HRID 214944

Reaction equation

HRID 214944 reaction equation
[ClH:1].[O:18]=[C:19]1[CH2:20][CH2:21][c:22]2[c:23]([C:35]([F:36])([F:37])[F:38])[cH:24][c:25]([O:29][CH2:30][CH2:31][CH2:32][CH:33]=[O:34])[n:26][c:27]2[NH:28]1.[c:2]1([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12>>[c:2]1([N:12]2[CH2:13][CH2:14][N:15]([CH2:33][CH2:32][CH2:31][CH2:30][O:29][c:25]3[cH:24][c:23]([C:35]([F:36])([F:37])[F:38])[c:22]4[c:27]([n:26]3)[NH:28][C:19](=[O:18])[CH2:20][CH2:21]4)[CH2:16][CH2:17]2)[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 13421-(1-Naphthyl)piperazineHCID 210733764-(7-Oxo4-trifluoromethyl-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde

Product 1

HCID 210738137-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butoxy]-5-trifluoromethyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Sources & evidence

ORD record
ord-798088e9d67443468539c336ff4653cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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