Chloride → 5-Hydroxy-7-isopropyl-4-oxo-3,4-dihydrospiro[chromen-2,1'-cyclobutane]-6-carbaldehyde

Reaction equation

[CH3:19][O:20][CH:21]([Cl:22])[Cl:23].[Cl-:24].[Cl-:26].[Cl-:27].[Cl-:28].[Cl:29][CH2:30][Cl:31].[OH:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([CH:12]([CH3:13])[CH3:14])[cH:11]1)[O:7][C:6]1([CH2:5][C:4]2=[O:18])[CH2:15][CH2:16][CH2:17]1.[Ti+4:25]>>[OH:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([CH:12]([CH3:13])[CH3:14])[c:11]1[CH:19]=[O:20])[O:7][C:6]1([CH2:5][C:4]2=[O:18])[CH2:15][CH2:16][CH2:17]1

Participants

Reactant 5

HCID 312Chloride4×

HCID 6344Dichloromethane

HCID 21004Methane, dichloromethoxy-

HCID 114942Titanium cation (4+)

HCID 58002934HCID 58002934, compound

Product 1

HCID 580029765-Hydroxy-7-isopropyl-4-oxo-3,4-dihydrospiro[chromen-2,1'-cyclobutane]-6-carbaldehyde

Sources & evidence

ORD record: ord-5e28acc7f98840acaa082e4d7f34451a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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