Sodium Ion → Tert-butyl 3-(azidomethyl)-4-hydroxy-pyrrolidine-1-carboxylate

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:15])[CH:11]([CH2:13][OH:14])[CH2:12]1.[Cl:16][CH2:17][Cl:18].[N-:19]=[N+:20]=[N-:21].[Na+:22].[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:15])[CH:11]([CH2:13][N:19]=[N+:20]=[N-:21])[CH2:12]1

Participants

Reactant 5

HCID 923Sodium Ion

HCID 1049Pyridine

HCID 6344Dichloromethane

HCID 33558Azide

HCID 23125669tert-Butyl 3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 86651025Tert-butyl 3-(azidomethyl)-4-hydroxy-pyrrolidine-1-carboxylate

Sources & evidence

ORD record: ord-fed958ac51cb47e79d10cf483cf0f11c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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