Sodium Ion → 2-Iodo-6-methyl-4-(4-trifluoromethyl-phenyl)pyridine

Reaction equation

[Br:1][c:2]1[n:3][c:4]([CH3:18])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1.[CH3:21][NH:22][CH2:23][CH2:24][NH:25][CH3:26].[Cu:33][I:34].[I-:20].[Na+:19].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[c:2]1([I:20])[n:3][c:4]([CH3:18])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[cH:7]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 8070N,N'-Dimethylethylenediamine

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 30165Iodide Ion

HCID 312751,4-Dioxane

HCID 574686462-Bromo-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

Product 1

Sources & evidence

ORD record: ord-02165805064e4771ad120f935d0306fa
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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