N-methyl-2-pyrrolidone → 1-[6'-(5-Fluoro-2,3-dihydro-indole-1-carbonyl)-2'-methoxy-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl]-1,3-dihydro-imidazo[4,5-b]pyridin-2-one

HRID 2152260

Reaction equation

HRID 2152260 reaction equation
[CH3:38][N:39]1[CH2:40][CH2:41][CH2:42][C:43]1=[O:44].[Cl:17][c:18]1[cH:19][c:20]([C:26](=[O:27])[N:28]2[CH2:29][CH2:30][c:31]3[cH:32][c:33]([F:37])[cH:34][cH:35][c:36]32)[n:21][c:22]([O:24][CH3:25])[cH:23]1.[NH:1]1[CH2:2][CH2:3][CH:4]([n:7]2[c:8](=[O:16])[nH:9][c:10]3[n:11][cH:12][cH:13][cH:14][c:15]23)[CH2:5][CH2:6]1>>[N:1]1([c:18]2[cH:19][c:20]([C:26](=[O:27])[N:28]3[CH2:29][CH2:30][c:31]4[cH:32][c:33]([F:37])[cH:34][cH:35][c:36]43)[n:21][c:22]([O:24][CH3:25])[cH:23]2)[CH2:2][CH2:3][CH:4]([n:7]2[c:8](=[O:16])[nH:9][c:10]3[n:11][cH:12][cH:13][cH:14][c:15]23)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 22293182Bms-973013HCID 58386681HCID 58386681, compound

Product 1

HCID 583865521-[6'-(5-Fluoro-2,3-dihydro-indole-1-carbonyl)-2'-methoxy-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl]-1,3-dihydro-imidazo[4,5-b]pyridin-2-one

Sources & evidence

ORD record
ord-4d9be232795749b48e9348d44b25b6c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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