N-methyl-2-pyrrolidone → 3-(7-bromo-quinolin-4-yl)-2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-4-ol

HRID 2154037

Reaction equation

HRID 2154037 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6](-[c:12]3[c:13]4[n:14]([n:15][c:16]3-[c:17]3[n:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH2:24][CH:25]4[Cl:26])[cH:7][cH:8][n:9][c:10]2[cH:11]1.[CH3:27][N:28]1[CH2:29][CH2:30][CH2:31][C:32]1=[O:33]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6](-[c:12]3[c:13]4[n:14]([n:15][c:16]3-[c:17]3[n:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH2:24][CH:25]4[OH:33])[cH:7][cH:8][n:9][c:10]2[cH:11]1

Participants

3

Reactant 2

HCID 13387N-methyl-2-pyrrolidoneHCID 101132117-Bromo-4-(4-chloro-2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinoline

Product 1

HCID 101795483-(7-bromo-quinolin-4-yl)-2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-4-ol

Sources & evidence

ORD record
ord-69489a82ed04486b823faf230629227f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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