Hydrochloric Acid → 4-{2-[(3-Chlorophenoxy)acetyl]-1,2,3,4-tetrahydroisoquinolin-7-yl}-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

HRID 2158761

Reaction equation

HRID 2158761 reaction equation
[CH3:13][N:14]1[CH2:15][CH2:16][N:17]([c:20]2[n:21][c:22]([NH2:36])[n:23][c:24](-[c:26]3[cH:27][cH:28][c:29]4[c:34]([cH:35]3)[CH2:33][NH:32][CH2:31][CH2:30]4)[cH:25]2)[CH2:18][CH2:19]1.[Cl:1][c:2]1[cH:3][c:4]([O:5][CH2:6][C:7](=[O:8])[Cl:9])[cH:10][cH:11][cH:12]1.[ClH:37]>>[Cl:1][c:2]1[cH:3][c:4]([O:5][CH2:6][C:7](=[O:8])[N:32]2[CH2:31][CH2:30][c:29]3[cH:28][cH:27][c:26](-[c:24]4[n:23][c:22]([NH2:36])[n:21][c:20]([N:17]5[CH2:16][CH2:15][N:14]([CH3:13])[CH2:19][CH2:18]5)[cH:25]4)[cH:35][c:34]3[CH2:33]2)[cH:10][cH:11][cH:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 70103393-Chlorophenoxyacetyl chlorideHCID 497794384-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine

Product 1

HCID 594967404-{2-[(3-Chlorophenoxy)acetyl]-1,2,3,4-tetrahydroisoquinolin-7-yl}-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-2c62178877e14259b72cbb0eb285312a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Linked notes

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