Hydrochloric Acid → 1-[5-[[5-Bromo-3-[(2-methyl-3-pyridinyl)oxy]-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]ethane-1,2-diol

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([O:24][c:25]2[c:26]([CH3:31])[n:27][cH:28][cH:29][cH:30]2)[c:5]([NH:8][c:9]2[n:10][c:11]([CH:14]3[O:15][C:16]4([O:17][CH2:18]3)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]4)[n:12][s:13]2)[n:6][cH:7]1.[CH3:33][OH:34].[ClH:32]>>[Br:1][c:2]1[cH:3][c:4]([O:24][c:25]2[c:26]([CH3:31])[n:27][cH:28][cH:29][cH:30]2)[c:5]([NH:8][c:9]2[n:10][c:11]([CH:14]([OH:15])[CH2:18][OH:17])[n:12][s:13]2)[n:6][cH:7]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 67486321N-[5-bromo-3-[(2-methyl-3-pyridinyl)oxy]-2-pyridinyl]-3-(1,4-dioxaspiro[4.5]decan-3-yl)-1,2,4-thiadiazol-5-amine

Product 1

HCID 723007241-[5-[[5-Bromo-3-[(2-methyl-3-pyridinyl)oxy]-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]ethane-1,2-diol

Sources & evidence

ORD record: ord-55b1e458562148a9bc1391a28080a4c0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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