O-(prop-2-yn-1-yl)hydroxylamine → HCID 136127200, compound
Reaction equation
[C:1]([C:6]1[C:7](=[O:23])[CH2:8][CH:9]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([S:21][CH3:22])=[O:20])=[CH:15][CH:14]=2)[CH2:10][C:11]=1[OH:12])(=O)[CH2:2][CH2:3][CH3:4].[CH2:24]([O:27][NH2:28])[C:25]#[CH:26]>O1CCCC1>[OH:12][C:11]1[CH2:10][CH:9]([C:13]2[CH:14]=[CH:15][C:16]([C:19]([S:21][CH3:22])=[O:20])=[CH:17][CH:18]=2)[CH2:8][C:7](=[O:23])[C:6]=1[C:1](=[N:28][O:27][CH2:24][C:25]#[CH:26])[CH2:2][CH2:3][CH3:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Into 20 ml of tetrahydrofuran was dissolved 2 g of 2-butyryl-3-hydroxy-5-[4-(methylthio)carbonylphenyl]-2-cyclohexen-1-one and to the solution was added 0.7 g of propargyloxyamine. The mixture was kept for 15 hours at room temperature and the solvent was distilled off from it under reduced pressure. Then, the residue was recrystallized with mixture solvent of benzene-ligroin and 1.6 g of colorless desired crystals having a melting point of 95°-96° C. were obtained.