Tetrahydrofuran → 2'-(((2,4'-Dichloro-2'-methyl-[1,1'-biphenyl]-4-yl)amino)methyl)-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid

Reaction equation

[OH-].[Na+].C1COCC1.[Cl:8][C:9]1[CH:14]=[C:13]([NH:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:18]=2[C:27]2[CH:32]=[CH:31][C:30]([C:33]([O:35]C)=[O:34])=[CH:29][CH:28]=2)[CH:12]=[CH:11][C:10]=1[C:37]1[CH:42]=[CH:41][C:40]([Cl:43])=[CH:39][C:38]=1[CH3:44]>CO>[Cl:8][C:9]1[CH:14]=[C:13]([NH:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:18]=2[C:27]2[CH:28]=[CH:29][C:30]([C:33]([OH:35])=[O:34])=[CH:31][CH:32]=2)[CH:12]=[CH:11][C:10]=1[C:37]1[CH:42]=[CH:41][C:40]([Cl:43])=[CH:39][C:38]=1[CH3:44]