Resveratrol → 5-(2-(4-Hydroxyphenyl)Ethenyl)Benzene-1,3-Diol

HRID 2170240

Reaction equation

HRID 2170240 reaction equation
[C:1]1(/[CH:9]=[CH:10]/[C:11]2[CH:17]=[CH:16][C:14]([OH:15])=[CH:13][CH:12]=2)[CH:8]=[C:6]([OH:7])[CH:5]=[C:3]([OH:4])[CH:2]=1.C([O-])(O)=O.[Na+]>C(O)C>[C:1]1([CH:9]=[CH:10][C:11]2[CH:17]=[CH:16][C:14]([OH:15])=[CH:13][CH:12]=2)[CH:8]=[C:6]([OH:7])[CH:5]=[C:3]([OH:4])[CH:2]=1

Participants

4

Reactant 2

HCID 445154ResveratrolHCID 516892Sodium Bicarbonate

Product 1

HCID 50565-(2-(4-Hydroxyphenyl)Ethenyl)Benzene-1,3-Diol

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

700 mg of trans-resveratrol (manufactured by Tokyo Chemical Industry Co., Ltd.) was dissolved in 14 ml of ethanol, and then 14 mL of a 2.5% NaHCO3 aqueous solution was added thereto to obtain a resveratrol containing solution (pH 9.9). The resveratrol containing solution was heated at 130° C. for 20 minutes in an autoclave (“SANYO LABO AUTOCLAVE” manufactured by SANYO Electric Co., Ltd., which was used in the following Examples). Subsequently, 14 ml of ethanol and 14 mL of a 5.0% NaHCO3 aqueous solution were added to the reaction solution obtained by the first autoclave treatment, and then heated again at 130° C. for 20 minutes in the autoclave. Then, 1 mL of the obtained reaction solution was diluted with methanol in a measuring cylinder to 50 mL, and then 10 L, thereof was analyzed by HPLC.

Sources & evidence

ORD record
ord-74c3a81a4de34061a5520bedb7187f05
Source dataset
uspto-grants-2015_06
Patent number
US09051245B2

Linked notes

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