Pyrrolidine → 8-Pyrrolidinyloctylphthalimide

HRID 21812

Reaction equation

HRID 21812 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[CH:20]=[CH:19][CH:18]=[C:12]2[C:13]([NH:15][C:16](=[O:17])[C:11]=12)=[O:14].[NH:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1>C(OCC)C>[N:21]1([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]2[CH:20]=[CH:19][CH:18]=[C:12]3[C:13]([NH:15][C:16](=[O:17])[C:11]=23)=[O:14])[CH2:25][CH2:24][CH2:23][CH2:22]1

Participants

4

Reactant 2

HCID 31268PyrrolidineHCID 232906438-Bromooctylphthalimide

Product 1

HCID 542934218-Pyrrolidinyloctylphthalimide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

8-Bromooctylphthalimide (517 mg; 2.0 mmoles) and pyrrolidine (0.33 ml; 4.0 mmoles) were dissolved in anhydrous ethyl ether (5 ml). Reaction times and process as per Example 1.

Workup

  1. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-4da5932a953b47a0806b706fd516d3f9
Source dataset
uspto-grants-1995_06
Patent number
US05424451

Linked notes

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