2,2-Diphenylacetyl chloride → N-(2-Isopropyl-2H-tetrazol-5-yl)-2,2-diphenyl-acetamide

HRID 2184969Notes

Reaction equation

HRID 2184969 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][N:5]([CH:7]([CH3:9])[CH3:8])[N:6]=1.[C:10]1([CH:16]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:17](Cl)=[O:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH:7]([N:5]1[N:4]=[N:3][C:2]([NH:1][C:17](=[O:18])[CH:16]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[N:6]1)([CH3:9])[CH3:8]

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 47711312-(propan-2-yl)-2H-1,2,3,4-tetrazol-5-amine

Product 1

HCID 9944980N-(2-Isopropyl-2H-tetrazol-5-yl)-2,2-diphenyl-acetamide

Procedure

The title compound, white solid, m.p. 175-177° and MS: (neg. ions): m/e=320.2 (M+−H) was prepared in accordance with the general method of example 1 from 5-amino-2-isopropyl-2H-tetrazole and diphenylacetyl chloride.

Sources & evidence

ORD record
ord-eb5690f8931c4085ac95549bd90b90cc
Source dataset
uspto-grants-2002_06
Patent number
US06399641B1

Reaction notes

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