2-Bromopropane → HCID 20519071, compound

HRID 2198798

Reaction equation

HRID 2198798 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1.Br[CH:16]([CH3:18])[CH3:17]>O>[CH:3]1([CH2:2][O:1][CH:16]([CH3:18])[CH3:17])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]1

Participants

4

Reactant 2

HCID 63582-BromopropaneHCID 74686Cyclododecanemethanol

Product 1

HCID 20519071HCID 20519071, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

According to the disclosure of Example 1, 99 g of hydroxymethylcyclododecane was first converted into the sodium alcoholate. 74 g (0.6 mol) of 2-bromopropane was added dropwise to the boiling suspension, and then the mixture was heated for 30 hours under reflux. The reaction mixture was poured into water, the organic phase was washed with water, dried over Na2SO4, and then distilled.

Workup

  1. temperaturethe mixture was heated for 30 hours
  2. temperatureunder reflux
  3. washthe organic phase was washed with water
  4. dry with materialdried over Na2SO4
  5. distillationdistilled

Sources & evidence

ORD record
ord-dcbf17b5baba4e33805706cfee481f0a
Source dataset
uspto-grants-1982_11
Patent number
US04359588

Linked notes

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