Isobutyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid
Reaction equation
C(Cl)C(C)C.[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[CH:7]([CH3:12])[CH3:8].[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1Participants
4
Procedure
The titled compound (10 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and isobutyl chloride according to the method of the process (7) of Example 4.
Sources & evidence
- ORD record
- ord-89fff89f87f048c5aa6c298f4e4dbe3e