Iodoethane → HCID 178462537, compound
Reaction equation
[CH3:1][C:2]1[O:3][C:4]2[C:5]([N:10]=1)=[N:6][CH:7]=[CH:8][CH:9]=2.[CH2:11]([I:13])[CH3:12]>>[I-:13].[CH2:11]([N:6]1[CH:7]=[CH:8][CH:9]=[C:4]2[O:3][CH:2]([CH3:1])[NH+:10]=[C:5]12)[CH3:12]Participants
3
Procedure
This Example shows the preparation of exemplary compound Dye 9 and its physical properties. A mixture of 1.34 g (10 mmol) 2-methyl-oxazolo[4,5-b]pyridine and 2 ml ethyliodide in a closed system was kept 2 h at 110° C. The product was precipitated with acetone and filtered off. The yellow crystalline product was filtered off and washed with diethyl ether to provide 2.47 g (86%) 4-ethyl-2-methyl-oxazolo[4,5-b]pyridinium iodide, which was of sufficient purity to carry on to the next synthetic step.
Workup
- customthe preparation of exemplary compound Dye 9 and its physical properties
- customThe product was precipitated with acetone
- filtrationfiltered off
- filtrationThe yellow crystalline product was filtered off
- washwashed with diethyl ether
Sources & evidence
- ORD record
- ord-802c5e820c954d4da79a7c70dc36a8f2
- Source dataset
- uspto-grants-2016_06
- Patent number
- US09376568B2
Reaction notes
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