Hydrochloric Acid → HCID 21962078, compound
Reaction equation
[O:1]=[C:2]1[NH:8][CH2:7][CH2:6][CH2:5][N:4](C(OC(C)(C)C)=O)[CH:3]1[CH2:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][C:24]([F:27])([F:26])[F:25])=[CH:19][CH:18]=1.[ClH:28]>O1CCOCC1>[ClH:28].[F:27][C:24]([F:25])([F:26])[O:23][C:20]1[CH:21]=[CH:22][C:17]([CH2:16][CH:3]2[NH:4][CH2:5][CH2:6][CH2:7][NH:8][C:2]2=[O:1])=[CH:18][CH:19]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
tert-Butyl hexahydro-3-oxo-2-[4-(trifluoromethoxy)benzyl]-1H-1,4-diazepine-1-carboxylate was dissolved in 4M hydrogen chloride in dioxane and after 2.5 h evaporated to yield the desired product.
Workup
- customevaporated
Sources & evidence
- ORD record
- ord-2d31e8fe8d054ed0a310c35b55a9ef86
- Source dataset
- uspto-grants-2006_09
- Patent number
- US07101871B2
Reaction notes
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