Chloroformamidine hydrochloride → Cyanamide
Reaction equation
[ClH:1].[CH:2]([O:5][C:6](=[NH:8])[NH2:7])([CH3:4])[CH3:3].[Cl-].[Cl:10][C:11]([NH2:13])=[NH2+:12]>C(O)(C)C>[ClH:10].[CH:2]([O:5][C:6](=[NH:7])[NH2:8])([CH3:4])[CH3:3].[Cl-:1].[Cl:10][C:11]([NH2:13])=[NH2+:12].[N:7]#[C:6][NH2:8]Participants
6
Reactant 2
Product 3
Reagents, catalysts & solvents 1
Procedure
Furthermore, JP-A-9-12530 discloses a production method of O-isopropyl-isourea hydrochloride using chloroform amidinium chloride. According to this method, a high purity crystalline O-isopropyl-isourea hydrochloride is obtained at a yield of 82% by the reaction of chloroform amidinium chloride, cyanamide and isopropyl alcohol.
Sources & evidence
- ORD record
- ord-25b1802b7a29418b8f595e3ca1ed4611
- Source dataset
- uspto-grants-2006_09
- Patent number
- US07105694B2
Reaction notes
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