epsilon-CAPROLACTONE → Lactic acid hydroxycaproic acid

HRID 22151

Reaction equation

[CH3:1][C@@H:2]1[O:9]C(=O)[C@H](C)[O:5][C:3]1=[O:4].[C:11]1(=[O:18])[O:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[C:3]([OH:5])(=[O:4])[CH:2]([CH3:1])[OH:9].[OH:4][CH:12]([CH2:13][CH2:14][CH2:15][CH3:16])[C:11]([OH:17])=[O:18]

Participants

Reactant 2

HCID 10401epsilon-CAPROLACTONE

HCID 107983Lactide, L-

Product 1

HCID 86747420Lactic acid hydroxycaproic acid

Procedure

The same procedure as in Preparation Example 4 was effected except that 6 mols of L-lactide and 14 mols of ε-caprolactone were used, thereby obtaining a lactic acid-hydroxycaproic acid copolymer (hereinafter referred to as "PCLA2"). This PCLA2 had a weight average molecular weight of 72000, and a molar ratio of a lactic acid unit to a hydroxycaproic acid unit in the copolymer was 33 to 67.

Workup

customThe same procedure as in Preparation Example 4

Sources & evidence

ORD record: ord-8bd64f4ff23f4f9898dd95212128cc50
Source dataset: uspto-grants-1995_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE034984

Linked notes

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