Methylumbelliferone → 7-Methoxychroman-2-one

HRID 2215101

Reaction equation

HRID 2215101 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9](=[O:13])[O:10]2)=[CH:5][CH:4]=1>[Pd]>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][C:9](=[O:13])[O:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 10748Methylumbelliferone

Product 1

HCID 123898377-Methoxychroman-2-oneYield 96%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Compound 14A was prepared by hydrogenation of 7-methoxy-chromen-2-one catalyzed by 10% Pd/C in 96% yield. MS: 179 (M+1)+.

Sources & evidence

ORD record
ord-a8e644d4c6824d6e8ed16b6249af9af2
Source dataset
uspto-grants-2006_09
Patent number
US07109222B2

Linked notes

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