Hydrogen Bromide → HCID 178515992, compound

HRID 2216339

Reaction equation

HRID 2216339 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14]C)[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br>O>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([OH:14])[N:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 219422742-Benzyl-6-methoxypyridine

Product 1

HCID 178515992HCID 178515992, compoundYield 70.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 59 g of 2-benzyl-6-methoxypyridine and 200 ml of 47% hydrobromic acid was heated under stirring in an oil bath at 100° C. for 7 hours. After standing to cool, 250 ml of water was added and the resulting crystals were filtered, washed with water and dried under reduced pressure, to give 38.9 g of the title compound.

Workup

  1. temperaturewas heated
  2. temperatureto cool
  3. filtrationthe resulting crystals were filtered
  4. washwashed with water
  5. customdried under reduced pressure

Sources & evidence

ORD record
ord-8432c46a7bbf42feb057a7de3b73cea2
Source dataset
uspto-grants-2006_09
Patent number
US07112593B2

Linked notes

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