2-Amino-4-methylthiazole → HCID 11659866, compound
Reaction equation
C(O[C:4]([C:6]1[C:11]([NH:12][C:13]2[CH:14]=[N:15][CH:16]=[N:17][CH:18]=2)=[CH:10][CH:9]=[C:8]([CH3:19])[N:7]=1)=[O:5])C.[NH2:20][C:21]1[S:22][CH:23]=[C:24]([CH3:26])[N:25]=1>>[CH3:26][C:24]1[N:25]=[C:21]([NH:20][C:4]([C:6]2[C:11]([NH:12][C:13]3[CH:18]=[N:17][CH:16]=[N:15][CH:14]=3)=[CH:10][CH:9]=[C:8]([CH3:19])[N:7]=2)=[O:5])[S:22][CH:23]=1Participants
3
Procedure
The title compound, was prepared in accordance with the general method of Example 78, step 2 from 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid ethyl ester and 2-amino-4-methylthiazole to yield the final compound as an off-white solid, MS (ISP): m/e=327.1 (M+H+).
Sources & evidence
- ORD record
- ord-1cde8c89cf994677b5f1dcb0e9f075d5
- Source dataset
- uspto-grants-2008_08