Formic Acid → 3-(3,4-Dimethoxyphenyl)propionic acid

HRID 2227016

Reaction equation

HRID 2227016 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[C:12]2C(=O)OC(C)(C)[O:14][C:13]2=[O:21])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].C(O)=O>C(N(CC)CC)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][C:13]([OH:21])=[O:14])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

4

Reactant 2

HCID 284Formic AcidHCID 3703145-(3,4-Dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

Product 1

HCID 750193-(3,4-Dimethoxyphenyl)propionic acid

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

After weighing 14.6 g (0.05 mol) of 5-(3,4-dimethoxyphenylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (m.p.: 173° C.) to 50 ml of the mixture of formic acid and triethylamine prepared according to Example 1, the procedure described in Example 1 was followed.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-1d4a6e09e4f740589cf4bec7be7308c7
Source dataset
uspto-grants-1994_09
Patent number
US05350872

Linked notes

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